AAP News Vol. 13 No. 3 March 1997, p. 3
© 1997 American Academy of Pediatrics
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Rotavirus vaccine hope

Stefanie Dell' Aringa

An antibody against NSP4, a molecule that plays a role in the replication of life-threatening rotavirus, shows potential for reducing diarrhea in young mice, and holds hope for a more potent human vaccine, according to a recent study.

Rotaviruses are the leading cause of severe viral gastroenteritis in infants and animals, most often producing diarrhea in the young (6 months to 2 years in children, and up to 14 days in mice). Each year 870,000 infants in developing countries die from such viruses' dehydrating diarrhea.